Memory stability and flexibility across the lifetime

 

Our goal is to understand how memories are stably stored and flexibly updated across time and experience. We use a multilevel approach to investigate the dynamic neural mechanisms governing these complex processes in health and disease.

We use an interdisciplinary strategy to find converging evidence for how memories are stored and updated in the brain—leveraging calcium imaging, optogenetic, chemogenetics, electrophysiology, immediate-early gene tagging, and various behavioral assays.

We ask—and endeavor to answer—fundamental questions about how memories are stored in the brain. To fill critical gaps in knowledge and have an enduring impact on the field, together we:

  • Seek the most creative solutions in the context of rigorous experimentation

  • Welcome lab members and collaborators who bring diverse backgrounds, experiences, and perspectives, including expertise outside of neuroscience

  • Integrate converging and emerging approaches

  • Synthesize and synergize to devise new solutions

  • Openly share our tools, processes, and data