Publications

"Nothing in science has any value to society if it is not communicated" - Anne Roe

We believe it is our duty as scientists to openly communicate our findings and tools to the scientific community and the broader public. The Cai Lab is committed to accessible and transparent science.

2025 Denise Cai 2025 Denise Cai

Interneuron theta phase locking controls seizure susceptibility

Christenson Wick Z, Philipsberg PA, Kohler C, Lamsifer SI, Katanov E, Adam CD, Gordon KE, Feng Y, Vetere LM, Donnelly GC, Humphrey C, Cai DJ, Shuman T. (2025). bioRxiv

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2025 Denise Cai 2025 Denise Cai

Simultaneous dual-color calcium imaging in freely-behaving mice

Dong Z, Feng Y, Diego K, Baggetta AM, Sweis BM, Pennington ZT, Lamsifer SI, Zaki Y, Sangiuliano F, Philipsberg PA, Morales-Rodriguez D, Kircher D, Slesinger P, Shuman T, Aharoni D, Cai DJ. (2025). Science Advances

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2025 Denise Cai 2025 Denise Cai

Multiplexed, scalable analog recording of gene regulation dynamics over weeks using intracellular protein tapes

Zheng L, Yan Y, Zhou B, Lim J, Shi D, An B, Ko B, Klyder E, Pitchiaya S, Cai DJ, Boyden ES, Wei D, Liò P, Linghu C. (2025). bioRxiv

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2025 Denise Cai 2025 Denise Cai

A comprehensive suite for extracting neuron signals across multiple sessions in one-photon calcium imaging

Vergara P, Wang Y, Srinivasan S, Dong Z, Feng Y, Koyanagi I, Kumar D, Chérasse Y, Naoi T, Sugaya Y, Sakurai T, Kano M, Shuman T, Cai DJ, Yanagisawa M, Sakaguchi M. (2025). Nature Communications

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2025 Denise Cai 2025 Denise Cai

Neuron-specific glycine metabolism links transfer RNA epitranscriptomic regulation to complex behaviors

Blaze J, Evans VD, Pliego JAF, Unichenko P, Javidfar B, Heissel S, Alwaseem H, Pennington Z, Cai DJ, Molina H, Henneberger C. (2025). Biological Psychiatry Global Open Science

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Distinct changes to hippocampal and medial entorhinal circuits emerge across the progression of cognitive deficits in epilepsy

Feng Y, Diego KS, Dong Z, Wick ZC, Page-Harley L, Page-Harley V, Schnipper J, Lamsifer SI, Pennington ZT, Vetere LM, Philipsberg PA, Soler I, Jurkowski A, Rosado CJ, Khan NN, Cai DJ, Shuman T. (2025). Cell Reports

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2025 Denise Cai 2025 Denise Cai

REM refines and rescues memory representations: A new theory

Shuster AE, Morehouse A, McDevitt EA, Chen PC, Whitehurst LN, Zhang J, Sattari N, Uzoigwe T, Ekhlasi A, Cai DJ, Simon K, Niethard N, Mednick SC. (2025). Sleep Advances

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Medial entorhinal-hippocampal desynchronization parallels the emergence of memory impairment in a mouse model of Alzheimer's disease pathology

Vetere LM, Galas AM, Vaughan N, Feng Y, Wick ZC, Philipsberg PA, Liobimova O, Fernandez-Ruiz A, Cai DJ, Shuman T. (2025). bioRxiv

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