Publications
"Nothing in science has any value to society if it is not communicated" - Anne Roe
We believe it is our duty as scientists to openly communicate our findings and tools to the scientific community and the broader public. The Cai Lab is committed to accessible and transparent science.
Ensemble-specific deficit in neuronal intrinsic excitability in aged mice
Chen L, Francisco TR, Baggetta AM, Zaki Y, Ramirez S, Clem RL, Shuman T, Cai DJ (2023) Neurobiology of Aging
Minian: An open-source miniscope analysis pipeline
It all begins with an idea.
Dong Z, Mau W, Feng Y, Pennington ZT, Chen L, Zaki Y, Rajan K, Shuman T, Aharoni D, Cai DJ (2022) eLife
CCR5 closes the temporal window for memory linking
It all begins with an idea.
Shen Y, Zhou M, Cai DJ, Filho DA, Fernandes G, Cai Y, Kim N, Necula D, Zhou C, Liu A, Kang X, Kamata M, Lavi A, Huang S, Silva T, Heo WD, Silva AJ (2022) Nature
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A distinct signaling pathway in parvalbumin-positive interneurons controls flexible memory updating
Cai DJ, Shuman T (2022) Neuropsychopharmacology
Dynamic and heterogeneous neural ensembles contribute to a memory engram
It all begins with an idea.
Sweis BM, Mau W, Rabinowitz S, Cai DJ (2021) Current Opinion in Neurobiology
Neuronal Nsun2 deficiency produces tRNA epitranscriptomic alterations and proteomic shifts impacting synaptic signaling and behavior
It all begins with an idea.
Blaze J, Navickas A, Phillips HL, Heissel S, Plaza-Jennings A, Miglani S, Asgharian H, Foo M, Katanski CD, Watkins CP, Pennington ZT, Javidfar B, Espeso-Gil S, Rostandy B, Alwaseem H, Hahn CG, Molina H, Cai DJ, Pan T, Yao WD, Goodarzi H, Haghighi F, Akbarian S (2021) Nature Communications
ezTrack - A step-by-step guide to behavior tracking
Pennington ZT, Diego KS, Francisco TR, LaBanca AR, Lamsifer SI, Liobimova O, Shuman T, Cai DJ (2021) Current Protocols
Propranolol inhibits reactivation of fear memory
Pennington ZT, Cai DJ (2021) Biological Psychiatry
Breakdown of spatial coding and interneuron synchronization in epileptic mice
Shuman T, Aharoni D, Cai DJ, Lee CR, Chavlis S, Page-Harley L, Vetere LM, Feng Y, Yang CY, Mollinedo-Gajate I, Chen L, Pennington ZT, Taxidis J, Flores SE, Cheng K, Javaherian M, Kaba CC, Rao N, La-Vu M, Pandi I, Shtrahman M, Bakurin KI, Masmanidis S, Kakh MS, Poirazi P, Silva AJ, Golshani P (2020) Nature
The lab on lockdown: Thinking back and looking ahead
Poe GR, Cai DJ (2020) Nature Reviews Neuroscience
Creating space for synaptic formation – A new role for microglia in synaptic plasticity
Zaki Y, Cai DJ (2020) Cell
The role of intrinsic excitability in the evolution of memory: Significance in memory allocation, consolidation, and updating
Chen L, Cummings KA, Mau W, Zaki Y, Dong Z, Rabinowitz S, Clem RL, Shuman T, Cai DJ (2020) Neurobiology of Learning and Memory
The brain in motion: How ensemble fluidity drives memory-updating and flexibility
Mau W, Hasselmo ME, Cai DJ (2020) eLife
ezTrack: An open-source video analysis pipeline for the investigation of animal behavior
Pennington ZT, Dong Z, Bowler R, Feng Y, Vetere LM, Shuman T, Cai DJ (2019) Scientific Reports
Human memories can be linked by temporal proximity
It all begins with an idea.
Yetton BD, Cai DJ, Spoormaker VI, Silva AJ, Mednick SC (2019) Frontiers in Human Neuroscience
CCR5 is a suppressor for cortical plasticity and hippocampal learning and memory
Zhou M, Greenhill S, Huang S, Silva TK, Sano Y, Wu S, Cai Y, Nagaoka Y, Sehgal M, Cai DJ, Lee YS, Fox K, Silva AJ (2016) eLife
Molecular and cellular mechanisms for trapping and activating emotional memories
Rogerson T, Jayaprakash B, Cai DJ, Sano Y, Lee Y, Bekal P, Deisseroth K, Silva AJ (2016) PLOS ONE
A shared neural ensemble links distinct contextual memories encoded close in time
Cai DJ, Aharoni D, Shuman T, Shobe J, Biane J, Song W, Wei B, Veshkini M, La-Vu M, Lou J, Flores S, Kim I, Sano Y, Zhou M, Baumgaertel K, Lavi A, Kamata M, Tuszynski M, Mayford M, Golshani P, Silva AJ (2016) Nature
Synaptic clustering within dendrites: An emerging theory of memory formation
Kastellakis G, Cai DJ, Mednick SC, Silva AJ, Poirazi P (2015) Progress in Neurobiology
CREB regulates memory allocation in the insular cortex
Sano Y, Shobe JL, Zhou M, Huang S, Shuman T, Cai DJ, Golshani P, Kamata M, Silva AJ (2014) Current Biology